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Professor Bushra Ateeq
PhD (Aligarh Muslim University)
Professor & Joy Gill Chair Senior Fellow, DBT/Wellcome Trust India Alliance Department of Biological Sciences & Bioengineering (BSBE)
Research Interest
Dr. Ateeq’s group is primarily interested in exploring the genetic and epigenetic changes that initiate cancer and its progression by employing novel strategies and approaches. Her overarching goal is to identify the molecular events that drive cancer and facilitate the process of acquiring resistance to chemotherapeutic drugs, in hopes that these discoveries can lead to the development of effective therapies against specific causative pathways.
Education
PhD, Aligarh Muslim University,2003
MSc, Aligarh Muslim University,1997
BSc, Aligarh Muslim University,1995
Selected Publications
Goel S, Bhatia V, Kundu S, Biswas T, Carskadon S, Gupta N, Asim M, Morrissey C, Palanisamy N, Ateeq B*. Transcriptional network involving ERG and AR orchestrates Distal-Less Homeobox-1 mediated prostate cancer progression. Nature Communications. 2021 Sep 7;12(1):5325.
Tiwari R#, Manzar N#, Bhatia V, Yadav A, Nengroo MA, Datta D, Carskadon S, Gupta N, Sigouros M, Khani F, Poutanen M, Zoubeidi A, Beltran H, Palanisamy N, Ateeq B*. Androgen Deprivation Upregulates SPINK1 Expression and Potentiates Cellular Plasticity in Prostate Cancer. Nature Communications. 2020 Jan 20;11(1):384.
Singh A, Srivastava N, Yadav A, Ateeq B*. Targeting AGTR1/NF-κB /CXCR4 axis by miR-155 attenuates oncogenesis in Glioblastoma. Neoplasia. 2020 Sep 4;22(10):497-510.
Bhatia V, Yadav A, Tiwari R, Nigam S, Goel S, Carskadon S, Gupta N, Goel A, Palanisamy N, Ateeq B*. Epigenetic silencing of miRNA-338-5p and miRNA-421 drives SPINK1-positive prostate cancer. Clinical Cancer Research. 2019 May 1;25(9):2755-2768.
Nunes JJ, Pandey SK, Yadav A, Goel S, Ateeq B*. Targeting NF-kappa B signaling by Artesunate restores sensitivity of castrate-resistant prostate cancer cells to anti-androgens. Neoplasia. 2017 Apr;19(4):333-345.
Tiwari R, Pandey SK, Goel S, Bhatia V, Shukla S, Jing X, Dhanasekaran SM, Ateeq B*. SPINK1 promotes colorectal cancer progression by downregulating Metallothioneins expression. Oncogenesis. 2015 Aug 10;4:e162.
Awards & Fellowships
Sun Pharma Science Foundation Research Award (2021) in the Medical Sciences - Basic Research category.
Elected Fellow (2021) of the Indian Academy of Sciences (IASc), Bangalore.
Elected Fellow (2021) of the National Academy of Sciences, India (NASI).
Shanti Swarup Bhatnagar Prize for Science and Technology in Medical Sciences (2020) by the Council of Scientific and Industrial Research (CSIR), Government of India.
Ramachandran-National Bioscience Award for Career Development (2020-21) by the Department of Biotechnology (DBT), Government of India.
OPPI Scientist Award – 2021 by the Organization of Pharmaceutical Producers of India (OPPI).
CSIR-Central Drug Research Institute Award (2020) for the excellence in Drug Research in Life Sciences category by CSIR-Central Drug Research Institute, Lucknow, India.
Basanti Devi Amir Chand Prize in Biomedical Sciences (2019) by the Indian Council of Medical Research (ICMR), Government of India.
Intermediate Fellowship Award from the Welcome Trust/ DBT India Alliance (2013 – 2019).
CNR Rao Faculty Award for the Excellence in Research conferred by IIT Kanpur (2019)
Professional Experience
Research Associate – DBT (2003-04), Department of Biochemistry, All India Institute of Medical Sciences, New Delhi, India
Research Associate – CSIR (2004-05), National Institute of Immunology, New Delhi, India.
Postdoctoral Research Fellow (2005-07), McGill University, Montreal, Canada.
Postdoctoral Research Fellow (2008-11), Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI.
Research Investigator (2011-13), Michigan Center for Translational Pathology, Department of Pathology, University of Michigan, Ann Arbor, MI.