Quick Links
K. Subramaniam
PhD (IISc Bangalore)
Professor, Department of Biological Sciences & Bioengineering (BSBE)
Research Interest
Adult stem cells; biology of germ cells; plant-parasitic nematodes Our laboratory investigates mechanisms that control mitosis-meiosis decision in the free-living nematode Caenorhabditis elegans. Using this system as a paradigm, our ultimate goal is to understand how self-renewal and differentiation decisions are controlled in adult stem cells. We also pursue an RNAi approach to understand the biology of plant-parasitic nematodes to ultimately develop novel pest control strategies.
Office
Department of BSBE
IIT Kanpur,
Kanpur 208016
Education
PhD, Indian Institute of Science, 1994
M.Sc., University of Madras, 1988
B.Sc., Bharathiyar, University, 1985
Selected Publications
S. Vaid, M. Ariz, A. Chaturbedi, G. Anil Kumar, and K. Subramaniam 2013. PUF-8 negatively regulates RAS/MAPK signalling to promote differentiation of C. elegans germ cells. Development 140: 1645-1654.
K. Pushpa, G. Anil Kumar, and K. Subramaniam 2013. PUF-8 and TCER-1 are essential for normal levels of several mRNAs in the C. elegans germline. Development 140: 1312-1320.
M. Ariz, M. Rana and K. Subramaniam 2009. C. elegans RNA-binding proteins PUF-8 and MEX-3 function redundantly to promote germline stem cell mitosis. Developmental Biology, 326: 295-304.
S. Jadhav, M. Rana and K. Subramaniam 2008. Multiple maternal proteins coordinate to restrict the translation of C. elegans nanos-2 to primordial germ cells. Development 135: 1803-1812.
B. C. Yadav, K. Veluthambi, and K. Subramaniam 2006. Host-generated double stranded RNA induces RNAi in plant-parasitic nematodes and protects the host from infection. Mol and Biochem Parasit 148: 219-222.
Awards & Fellowships
The Wellcome Trust International Senior Research Fellow, 2003-2009.